Well setup points is largely something you discover on your own or should test out on your own because you might handle certain types of spin better or worse than others. So it's a personal preference thing. You should go experiment.
That being said, as a lefty penholder, I'll give you a couple of mine.
Setup 1: The Poor man's Hezhiwen. (Note: this is when facing a righty)
Serving FH from your back corner. Give them pendulum serve, either side, or side/back, or side/top wide curving off the table away from them. The ball should really break wide. Unless the player is standing more middle of the table prior to the receive, they will have to reach to get this ball and you simply block or attack their weak shot cross court. Just youtube "the best of hezhiwen" and you'll see what I mean.
You should also have a good down the line serve with variation as a change up if they're cheating over too much on serve.
Setup 2: My personal favorite and number 1 go to play right now. Courtesy of NL giving me this one.
It's real simple and that's what I like about it.
Serving FH from your back corner. Serve down the to their backhand heavy backspin. The serve should really be loaded. On this serve I don't even try to hide what I'm doing all that much. I'm just focusing on making it as heavy as possible. If they feel comfortable looping heavy backspin with their backhand and can get it in consistently, congratulations. You're playing a quality player and get ready to buckle up. Or you can try the serve short. But in my experience, most players under 2000 (and even some 2000 ones) will push this ball. This is why I like to serve it long. It's hard to push or chop that service receive and keep it not go long off the table. Once it does, you FH loop that backspin ball (must have a good FH loop to do this) no questions asked. Generally with your powerful loop and their backspin, you'd be amazed how much of a hard time players have keeping this ball on the table. From there just mixed in the occasional dead ball serve that looks like your backspin and you'll get a few pushes long off the table here & there if you're luckly.
The beauty of this setup is that it's all about getting a predictable return. You only have to get good at 1 type of spin in this setup. Good vs looping backspin. To me it simplifies the game sometimes vs having 20 different type of serves & spins where you get 20 different type of spins in return. Just my 2 cents.
I'm sure others will have some tips but those are the two I'm primarily enjoying right now.