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In this Lancet paper, it said, "Nine participants (two [6%] in the low dose group, two [6%] in the middle dose group, and five [14%] in the high dose group) had an episode of severe fever (grade 3) with axillary temperature greater than 38·5°C." In the supplementary results, it summarized that...

Editor’s Pick The first COVID-19 vaccine to reach phase 1 clinical trial has been found to be safe, well-tolerated, and able to generate an immune response against SARS-CoV-2 in humans, according to an Article published in The Lancet. The open-label trial in 108 healthy adults demonstrates...

Coronavirus vaccine trials have their first results — but their promise is still unclear Scientists urge caution over hints of success emerging from small human and animal studies. https://www.nature.com/articles/d41586-020-01092-3 You may notice that Moderna stock price dropped ~10% today...

A study in Israel looked at COVID patients born +/- 3 years from 1982 because they stopped nationwide BCG vaccination since 1982. The result didn't show statistically significant difference between vaccinated and unvaccinated groups. It doesn't mean BCG vaccine trials won't work at all, because...

This study in Cell tested the immune response (not necessarily antibody response) against COVID from people never exposed to COVID and observed cross-reactivity as people were infected with common cold coronaviruses...

Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2766086 an online risk score calculator developed by Guangzhou from chest radiography...

Baal has explained a lot about antibodies, I want to add some points. 1. Can a blood test tell people if they have protective antibodies (Abs) against COVID-19? When people are infected by SARS-CoV-2, many types and kinds of Abs will be produced. Most (all?) of them are binding Abs, which...

Some right winger I know said this violated free speech lol https://www.aaem.org/resources/statements/joint-endorsed/physician-misinformation AAEM-ACEP Joint Statement on Physician Misinformation The American Academy of Emergency Medicine (AAEM) and the American College of Emergency Physicians...

https://www.sciencedirect.com/science/article/pii/S0924857920301643 The details of the French study to reveal an unexpected early COVID case in Dec

A great lecture on infectious diseases from Ian Lipkin to general audience

I am glad that people who are in charge realize the importance of the sampling and possible false negative! You know how China is dealing with the suspected case (i.e, exposure history, close contact) who tested negative in the first time? Make a second test... I know certain hospitals do make...

I think if someone rejects the man-made theory, one should also reject the lab leak theory. There are ~1200 nucleotide difference between the most close bat coronavirus RaTG13 (corrected: collected in Wuhan Institute of Virology in 2013) and SARS-CoV-2. The average mutation rate of SARS-CoV-2 is...

Pretty impressive, JBS in Texas! https://www.politico.com/magazine/story/2017/07/16/the-john-birch-society-is-alive-and-well-in-the-lone-star-state-215377 “We must teach our children their heritage,” Collins tells the crowd. “We’ve slowly forgotten our principles.” But there is a powerful...

https://www.npr.org/2020/04/29/847870532/what-the-u-s-might-learn-from-chinas-approach-to-covid-19 An interesting NPR interview with NYTimes health and science reporter McNeil. I wonder if the kind of healthy cert app he mentioned which is widely used in certain US industry will be adapted for...

High D-dimer level in blood was discussed by front line doctors early on and they regarded it as one of the indicators of poor prognosis. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30566-3/fulltext published on Mar 11 The potential risk factors of older age, high SOFA...

Several remdesivir trial results are out today! "Remdesivir" was translated into Chinese by many investors as "people's hope", and Bruce Aylward, WHO's expert team head who led investigation in China, said "There is only one drug right now that we think may have real efficacy and that's...

I doubt Economist's NYC stat is right. I've once downloaded confirmed/probable COVID deaths report from NYC. By Apr 13, 6589 confirmed COVID deaths and 3778 probable COVID deaths (COVID on death cert but PCR result pending). From Mar 11-Apr 13, 8184 deaths not to be known as confirmed or COVID...

I guess it was not unacceptable, right? She was able to get eggs and beef with community bulk purchase and get bread from the inner convenience store. I am not sure if she has a car. With suspended public transportation, it was hard to get around. I just did a quick search on youtube for wuhan...

My local community invited a family doctor to give a lecture on COVID in early Apr. He talked about how important Vitamin D is to keep a good immune system. Then he said COVID was a big flu and didn't kill many. Well, I am not against taking VC and VD for COVID prevention. I believe healthy...

What does Wuhan lockdown mean to solve the problem? Divide and conquer. If you don't have the capacity like Wuhan did to isolate all COVID cases into designated hospitals/makeshift hospitals/stadium hospitals/isolation hotels, track them - let them report symptoms every day, construct them to go...