One of my favorite setups at the moment is Stiga infinity with 39 degrees H3 Neo on FH and Xiom Vega Pro 2mm on BH. My racket is about 180g, average weight. This setup is not super fast. It has good control, but has a fairly high top gear. It's great for topspin attacks from both FH and BH. Blocking is great too. It has little vibration and decent feeling (although not as good as something like Nittaku Acoustic).
H3 Neo is great for service, short game, and topspin. Lifting backspin is super easy. However, if you are not familiar with hard tacky rubbers like H3 Neo, you will struggle at first. H3 Neo is more sensitive to spin and requires more precision than Mark V, so it is noticeably less forgiving than Mark V.
Xiom Vega Pro is a fast tensor rubber. It should be similar to Donic Blue P1. It's great for lifting backspin and blocking with BH. Chopping is decent too, which I occasionally do over the table. Vega Pro is also great for flips and loops, but my techniques are not consistent enough at the moment.
Overall, this is a great setup. To me, there isn't any serious drawbacks. But keep in mind that this racket will probably be heavier than your current one, as H3 Neo and Vega Pro are both heavier than Mark V (which is a light rubber).