Not very similar rubbers imo, first and foremost Nuzn50 is an almost-hybrid and V22DE is a purebred Euro style rubber
N50 is more comparable to V15Sticky, but I think it is even slower than V15Sticky. The grip and arc generation of N50 is better than both V22DE and V15S but it felt like N50 just wasn't as responsive. N50 felt more sensitive to spin as well, though playing short and over the table did feel more manageable with N50