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  1. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    I'm honestly not sure. My expertise is in cellular physiology and molecular pharmacology, not epidemiology or economics. Ask me about drugs or disease mechanisms or molecular biology, how blood vessels or kidneys work, or fibrosis and inflammation, my opinion has some value maybe. I don't run...
  2. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    We're contingency planning on how to teach first year medical students this summer in case we need to still use some sort of social distancing. I agree 100% with the previous post. State authorities should probably do similar screens on as big a scale possible once NIH proves the concept.
  3. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Open up too soon and it comes back with a vengeance setting us back further by every consideration. The problem is that we are flying blind, at least in the US. We have no strong data on where we are just yet. How many people have or have had this virus? What are the rational criteria needed...
  4. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Let's hope that is true everywhere, but I wouldn't minimize this. It's worth noting that 4,000 people died of this in the US in two days, and that is probably an undercount.
  5. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    The official numbers in Greater Houston area this morning are 5,293 cases, 81 deaths, 890 recovered. That encompasses several counties. In the city of Houston proper it is supposedly 2,124 cases, 16 deaths and 214 recovered. In reality it is pretty much impossible to know how many people are...
  6. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    I didnt know you were in Dallas. We are shut down too, for 3+ weeks now. There is still hospital capacity in Houston, which is a little hotter of a Covid-19 spot than Dallas at the moment, but my colleagues are nervous that this could change quickly. As you know, in Texas testing is at best...
  7. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Ha ha. Then I indeed welcome the distinction on behalf of all eggheads.
  8. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    The issue of SARS-CoV-2 being able to evade immune surveillance in part by suppressing interferon production (which was suggested by other studies too) MAY be a reason why ivermectin could be useful clinically Also interferon beta infusion which is currently in clinical trial for Covid-19 and...
  9. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Some data on an anti-viral. Not a controlled trial but promising. Just came out in New England Journal of Medicine. These were very very sick patients. The paper includes a lot of detail on the outcomes. Compassionate Use of Remdesivir for Patients with Severe Covid-19 Jonathan Grein...
  10. What is the best alternative for Tenergy 05?

    That's it. I play better with that kind of rubber. It definitely punishes lazy technique though. It is pretty much the opposite of T05.
  11. What is the best alternative for Tenergy 05?

    It is a bit like Stiga Mantra. Korean brand.
  12. What is the best alternative for Tenergy 05?

    Nexy Karis. Very different from T05!!!!!! I like it, a lot of people will think I'm crazy.
  13. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Disturbing evidence is emerging of sudden cardiac deaths in Covid-19 patients, so chloroquine, which can induce arrythmias will need to be used very carefully. Regarding ventilators, a colleague of mine told me that in ARDS caused by influenza survival rate on a ventilator is somewhere around...
  14. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Yep. Also a very safe drug, used effectively by people in parts of the world where there are almost no doctors to treat similar parasitic infections that occur in humans. But at the moment no evidence at all of in vivo (in a person or animal, not a test tube) activity against any virus. Which...
  15. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Yes, that was my thought too, so I did a little more digging into the literature. Apparently the main effect in the case of coronavirus is that inhibition of nuclear import helps it evade human immune responses. The pathways are fairly complex but include multiple transcription factors that...
  16. What is the best alternative for Tenergy 05?

    There is no alternative but you might play just as well or even better with something else. But it will feel different. Nobody has cloned it the way people have cloned, say, Butterfly ALC blades. As Carl said, the sponge is completely unique. Only wsy to know if something else suits you is...
  17. What is the best alternative for Tenergy 05?

    We should all contemplate Rule 88 in these difficult times.
  18. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    Indomethacin is an NSAID. It's a problem when we dont even have proper case reports to go on, but see below. Until its resolved I wouldn't use it. ------------- March 17, 2020 -- A warning from French health officials suggests that grave adverse events have been reported with the use of...
  19. What is the best alternative for Tenergy 05?

    There is no alternative to Tenergy 05. Stop asking.
  20. SARS-CoV-2; CoVID-19; Coronavirus; Updates and Information

    I'm not an MD. I am a PhD (in pharmacology) and I do medical research. I can't really advise you on that. Bear in mind that it is completely unproven.
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